Stem cell regenerative therapy in alveolar cleft reconstruction

Highlights • We report on advances in alveolar cleft reconstruction using stem cells. • We summarize pros and cons of stem cell sources, scaffolds and growth factors. • Long-term data and detailed follow-up studies are crucial for further development. • Stem cell-based tissue engineering holds promi...

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Bibliographic Details
Published in:Archives of oral biology 2015-10, Vol.60 (10), p.1517-1532
Main Authors: Gładysz, Dominika, Hozyasz, Kamil K
Format: Article
Language:English
Subjects:
Advanced Basic Science
Alveolar Bone Grafting - methods
Alveolar cleft
Animals
Bone regeneration
Bone Transplantation - methods
Cleft palate
Dentistry
Humans
Mesenchymal stem cells
Reconstructive Surgical Procedures - methods
Stem Cell Transplantation - methods
Tissue engineering
Tissue Engineering - methods
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Summary:Highlights • We report on advances in alveolar cleft reconstruction using stem cells. • We summarize pros and cons of stem cell sources, scaffolds and growth factors. • Long-term data and detailed follow-up studies are crucial for further development. • Stem cell-based tissue engineering holds promise for improving quality of life.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2015.07.003