Optimal duration of an early intervention programme for first-episode psychosis: randomised controlled trial

Numerous early intervention services targeting young people with psychosis have been established, based on the premise that reducing treatment delay and providing intensive treatment in the initial phase of psychosis can improve long-term outcome. To establish the effect of extending a specialised e...

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Bibliographic Details
Published in:British journal of psychiatry 2015-06, Vol.206 (6), p.492-500
Main Authors: Chang, Wing Chung, Chan, Gloria Hoi Kei, Jim, Olivia Tsz Ting, Lau, Emily Sin Kei, Hui, Christy Lai Ming, Chan, Sherry Kit Wa, Lee, Edwin Ho Ming, Chen, Eric Yu Hai
Format: Article
Language:English
Subjects:
Adolescent
Adult
Cognitive Therapy - methods
Combined Modality Therapy - methods
Female
Humans
Male
Psychotherapy - methods
Psychotic Disorders - therapy
Single-Blind Method
Time Factors
Treatment Outcome
Young Adult
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Summary:Numerous early intervention services targeting young people with psychosis have been established, based on the premise that reducing treatment delay and providing intensive treatment in the initial phase of psychosis can improve long-term outcome. To establish the effect of extending a specialised early intervention treatment for first-episode psychosis by 1 year. A randomised, single-blind controlled trial (NCT01202357) compared a 1-year extension of specialised early intervention with step-down care in patients who had all received a 2-year intensive early intervention programme for first-episode psychosis. Patients receiving an additional year of specialised intervention had better outcomes in functioning, negative and depressive symptoms and treatment default rate than those managed by step-down psychiatric care. Extending the period of specialised early intervention is clinically desirable but may not be feasible in lower-income countries.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.bp.114.150144