Inhibition of Human Hepatitis B Virus Replication by AT-61, a Phenylpropenamide Derivative, Alone and in Combination with (−)β-l-2′,3′-Dideoxy-3′-Thiacytidine

• Published in: Antimicrobial Agents and Chemotherapy 1998-12, Vol.42 (12), p.3179-3186
• Main Authors: King, R W, Ladner, S K, Miller, T J, Zaifert, K, Perni, R B, Conway, S C, Otto, M J
• Format: Article
• Language: English
• Subjects: Amides; Amides - pharmacology; Antiviral Agents; Antiviral Agents - pharmacology; Benzene Derivatives; Benzene Derivatives - pharmacology; Cell Line; Cell Survival - drug effects; DNA, Viral - biosynthesis; Drug Resistance, Microbial; Drug Synergism; Hepatitis B virus; Hepatitis B virus - drug effects; Humans; Lamivudine; Lamivudine - pharmacology; Nucleic Acid Synthesis Inhibitors; Ribonucleases - metabolism; RNA-Directed DNA Polymerase - metabolism; Tetracyclines - pharmacology; Transfection; Viral Plaque Assay; Virus Replication - drug effects
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.42.12.3179

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