The clinical utility of HIV outpatient pharmacist prescreening to reduce medication error and assess adherence

Antiretroviral therapy (ART) is complex and has high propensity for medication error and drug-drug interactions (DDIs). We evaluated the clinical utility of pharmacist prescreening for DDIs, adherence to ART and medicines reconciliation prior to HIV outpatient appointments. A pharmacist took detaile...

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Bibliographic Details
Published in:International journal of STD & AIDS 2013-03, Vol.24 (3), p.237-241
Main Authors: Seden, K, Bradley, M, Miller, A R O, Beadsworth, M B J, Khoo, S H
Format: Article
Language:English
Subjects:
Adult
Aged
Anti-Retroviral Agents - adverse effects
Anti-Retroviral Agents - therapeutic use
Drug Interactions
Female
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Male
Medication Adherence
Medication Errors - prevention & control
Middle Aged
Outcome Assessment (Health Care)
Outpatient Clinics, Hospital
Pharmaceutical Services
Pharmacists
Professional Role
Referral and Consultation
Young Adult
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Summary:Antiretroviral therapy (ART) is complex and has high propensity for medication error and drug-drug interactions (DDIs). We evaluated the clinical utility of pharmacist prescreening for DDIs, adherence to ART and medicines reconciliation prior to HIV outpatient appointments. A pharmacist took detailed medication histories and ART adherence assessments, then screened medication for DDIs. A template detailing current medication, potential DDIs and adherence was filed in the clinical notes and physicians were asked for structured feedback. Potential DDIs were observed in 58% of 200 patients, with 22 (9%) potential DDIs occurring with medication that was not previously recorded in the patients’ notes. Of 103 physician responses, 61.2% reported that the pharmacist consultation told them something they did not know, and pharmacist consultants led to change in management in 13.6% of cases. Pharmacist consultations were more likely to add benefit in patients taking two or more concomitant medications in addition to ART (P = 0.0012).
ISSN:0956-4624
1758-1052
DOI:10.1177/0956462412472428