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Inhibition of Na super(+)/K super(+)-ATPase and of active ion-transport functions in the gills of the shore crab Carcinus maenas induced by cadmium

Inhibition of Na super(+)/K super(+)-ATPase from gill plasma membranes of the shore crab Carcinus maenas by cadmium was investigated and compared with inhibitory effects by known antagonists (ouabain and Ca super(2+)). For comparative considerations the Cd super(2+)-inhibition of the enzyme from dog...

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Bibliographic Details
Published in:Marine biology 1997-03, Vol.130 (3), p.407-416
Main Authors: Postel, U, Petrausch, G, Riestenpatt, S, Weihrauch, D, Malykh, J, Becker, W, Siebers, D
Format: Article
Language:English
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Summary:Inhibition of Na super(+)/K super(+)-ATPase from gill plasma membranes of the shore crab Carcinus maenas by cadmium was investigated and compared with inhibitory effects by known antagonists (ouabain and Ca super(2+)). For comparative considerations the Cd super(2+)-inhibition of the enzyme from dog kidney was also tested. Na super(+) /K super(+)-ATPase from dog kidney and from crab gill differed greatly in sensitivity against ouabain. The inhibition constant K sub(i) of the dog enzyme amounted to 9.1 x 10 super(-7) mol/l, i.e. more than 300-fold smaller than the K sub(i) of 2.9 x 10 super(-4) mol/l determined for the crab enzyme.
ISSN:0025-3162