Oncologic outcomes of supratracheal laryngectomy: Critical analysis

Background Laryngeal cancer management should pursue function‐sparing therapeutic options. Even though demolitive surgery provides better control of disease at intermediate to advanced stages when compared to chemoradiotherapy, it does not preserve laryngeal function. Supratracheal partial laryngect...

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Published in:Head & neck 2015-10, Vol.37 (10), p.1417-1424
Main Authors: Rizzotto, Giuseppe, Crosetti, Erika, Lucioni, Marco, Bertolin, Andy, Monticone, Valentina, Sprio, Andrea Elio, Berta, Giovanni Nicolao, Succo, Giovanni
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
aspiration pneumonia
Female
Humans
Laryngeal cancer
laryngeal function sparing protocol
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Laryngectomy - adverse effects
Laryngectomy - methods
Larynx - pathology
Larynx - surgery
Lung cancer
Male
Middle Aged
open partial laryngectomy
Retrospective Studies
supratracheal partial laryngectomy
Survival Analysis
Treatment Outcome
Young Adult
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Summary:Background Laryngeal cancer management should pursue function‐sparing therapeutic options. Even though demolitive surgery provides better control of disease at intermediate to advanced stages when compared to chemoradiotherapy, it does not preserve laryngeal function. Supratracheal partial laryngectomy has been described as a function‐sparing surgical technique for laryngeal cancer with subglottic extension. Methods In this retrospective study, we analyzed the clinical outcomes of 115 patients who underwent supratracheal partial laryngectomy. Results At 5 years, overall survival (OS), disease‐free survival (DFS), and locoregional control rates were 78.9%, 68.5%, and 69.6%, respectively; DFS and locoregional control prevalences were greatly affected by pT4a classification (49.0% and 51.4%, respectively); and laryngeal function preservation was maintained in 78.3% of patients despite being affected by pT4a classification (59.3%) and age ≥65 (64.6%). Conclusion For cases with glottic tumors and with subglottic extension, the choice of supratracheal partial laryngectomy versus chemoradiotherapy can be considered to be effective in terms of prognostic and functional results. © 2014 Wiley Periodicals, Inc. Head Neck 37: 1417–1424, 2015
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.23773