The associations between triglyceride to high-density lipoprotein cholesterol ratios and the risks of gestational diabetes mellitus and large-for-gestational-age infant

Summary Objective To evaluate the associations between triglyceride to high‐density lipoprotein cholesterol (TG/HDL‐C) ratios and the risks of gestational diabetes mellitus (GDM) and delivering large‐for‐gestational‐age (LGA) infant. Design This was a single‐centre prospective observational study. P...

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Bibliographic Details
Published in:Clinical endocrinology (Oxford) 2015-10, Vol.83 (4), p.490-497
Main Authors: Wang, Dongyu, Xu, Shuqia, Chen, Haitian, Zhong, Lieqiang, Wang, Zilian
Format: Article
Language:English
Subjects:
Birth Weight - physiology
Cholesterol, HDL - blood
Diabetes, Gestational - blood
Female
Glycated Hemoglobin A - metabolism
Humans
Infant, Newborn
Male
Pregnancy
Prospective Studies
Triglycerides - blood
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Summary:Summary Objective To evaluate the associations between triglyceride to high‐density lipoprotein cholesterol (TG/HDL‐C) ratios and the risks of gestational diabetes mellitus (GDM) and delivering large‐for‐gestational‐age (LGA) infant. Design This was a single‐centre prospective observational study. Patients Six hundred and thirty‐six women with a singleton pregnancy were recruited. Measurements Lipids profile, HbA1c and glucose were measured at the time of oral glucose tolerance test (OGTT) during 24–28 gestational weeks. TG/HDL‐C ratios were calculated and clinical data including perinatal parameters were analysed. Results The prevalence of GDM was 17·30% (n = 110) and LGA was 3·93% (n = 25) in this study. TG/HDL‐C ratios were found to be significantly higher in GDM group (P 
ISSN:0300-0664
1365-2265
DOI:10.1111/cen.12742