Effect of different depths of anesthesia on postoperative cognitive function in laparoscopic patients: a randomized clinical trial

Postoperative cognitive dysfunction (POCD) is caused by many factors. This work was conducted to investigate the effect of different depths of anesthesia during combined intravenous-inhalational anesthesia on postoperative cognitive function in young and middle-aged laparoscopic patients. A total of...

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Bibliographic Details
Published in:Current medical research and opinion 2015-10, Vol.31 (10), p.1883-1887
Main Authors: Shu, Ai-Hua, Wang, Qiang, Chen, Xiao-Bo
Format: Article
Language:English
Subjects:
Adult
Anesthesia - methods
Anesthetics, Inhalation - administration & dosage
Bispectral index
Cognition - drug effects
Double-Blind Method
Female
Gynecologic Surgical Procedures - methods
Humans
Laparoscopic operation
Laparoscopy - methods
Methyl Ethers - administration & dosage
Middle Aged
Neuropsychological Tests
Piperidines - administration & dosage
Postoperative cognitive dysfunction
Postoperative Complications - epidemiology
Postoperative Period
Remifentanil
Sevoflurane
Young Adult
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Summary:Postoperative cognitive dysfunction (POCD) is caused by many factors. This work was conducted to investigate the effect of different depths of anesthesia during combined intravenous-inhalational anesthesia on postoperative cognitive function in young and middle-aged laparoscopic patients. A total of 192 patients scheduled for gynecologic laparoscopic operations were randomly divided into three groups. Anesthesia was maintained with inhalation of sevoflurane and infusion of remifentanil, which was adjusted to maintain bispectral index (BIS) at 30 
ISSN:0300-7995
1473-4877
DOI:10.1185/03007995.2015.1075968