Is peripheral blood or bone marrow a better source of stem cells for transplantation in cases of HLA-matched unrelated donors? A meta-analysis

Highlights • We performed a meta-analysis concerning HLA matched unrelated donor transplantation with peripheral blood or bone marrow. • The rate of engraftment (both neutrophil and platelet) and were higher in the PBSCT group. • No significant statistical differences were found on the rate of relap...

Full description

Saved in:
Bibliographic Details
Published in:Critical reviews in oncology/hematology 2015-10, Vol.96 (1), p.20-33
Main Authors: Wu, Sha, Zhang, Cheng, Zhang, Xi, Xu, Ya-qi, Deng, Tian-xia
Format: Article
Language:English
Subjects:
Bone marrow
Bone Marrow Transplantation
Hematology, Oncology and Palliative Medicine
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Peripheral blood
Peripheral Blood Stem Cell Transplantation
Transplantation Conditioning
Unrelated Donors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • We performed a meta-analysis concerning HLA matched unrelated donor transplantation with peripheral blood or bone marrow. • The rate of engraftment (both neutrophil and platelet) and were higher in the PBSCT group. • No significant statistical differences were found on the rate of relapse, 2-year overall survival (OS) and disease-free survival (DFS) after peripheral blood stem cell neither bone marrow transplantation (PBSCT and BMT).
ISSN:1040-8428
1879-0461
DOI:10.1016/j.critrevonc.2015.04.009