Effects Of Cag Repeat Polymorphism In The Androgen Receptor Gene On Fitness In Children

PURPOSE: To determine if androgen receptor polymorphism (CAG sub(n)) may influence body composition and the physical fitness in children. METHODS: The association between body fat mass and physical fitness with the AR CAG sub(n) polymorphism was studied in 250 physically active children, 145 boys an...

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Published in:Medicine and science in sports and exercise 2012-05, Vol.44 (5S), p.439-439
Main Authors: Rodriguez-Garcia, Lorena, Ponce-Gonzalez, Jesus G, Guadalupe-Grau, Amelia, Losa-Reyna, Jose, Rodriguez-Gonzalez, Francisco German, Dorado, Cecilia, Diaz-Chico, Bonifacio Nicolas, Calbet, Jose A L
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Language:English
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Summary:PURPOSE: To determine if androgen receptor polymorphism (CAG sub(n)) may influence body composition and the physical fitness in children. METHODS: The association between body fat mass and physical fitness with the AR CAG sub(n) polymorphism was studied in 250 physically active children, 145 boys and 105 girls (mean+ or -SD: 11.7+ or -2.6 and 10.2+ or -3.4 years old, respectively). The vertical jumping height (and power), running speed, and VO sub(2)max was determined in all subjects. RESULTS: The boys harboring CAG sub(S) achieved better running performance in the 300 m running test than their CAG sub(L) counterparts (71.0+ or -12.3 vs 74.2+ or -13.0, respectively; P=0.018). This difference remained statistically significant after accounting for height and age covariates. No statistically significant differences between CAG sub(S) and CAG sub(L) groups were found either in boys or in girls for the rest of the physical fitness variables.
ISSN:0195-9131