Computed tomography-guided percutaneous microwave ablation combined with osteoplasty for palliative treatment of painful extraspinal bone metastases from lung cancer

• Published in: Skeletal radiology 2015-10, Vol.44 (10), p.1485-1490
• Main Authors: Wei, Zhigang, Zhang, Kaixian, Ye, Xin, Yang, Xia, Zheng, Aimin, Huang, Guanghui, Wang, Jiao
• Format: Article
• Language: English
• Subjects: Ablation (Surgery); Aged; Aged, 80 and over; Bone Cements; Bone Neoplasms - complications; Bone Neoplasms - secondary; Bone Neoplasms - therapy; Bupivacaine; Care and treatment; Catheter Ablation; Combined Modality Therapy; CT imaging; Female; Follow-Up Studies; Health aspects; Humans; Imaging; Lung cancer; Lung Neoplasms - pathology; Male; Medicine; Medicine & Public Health; Metastasis; Microwaves; Middle Aged; Morphine; Nuclear Medicine; Orthopedics; Pain - etiology; Palliative Care - methods; Pathology; Radiography, Interventional; Radiology; Retrospective Studies; Scientific Article; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 0364-2348; 1432-2161
• DOI: 10.1007/s00256-015-2195-4

Objective To retrospectively evaluate the efficacy and safety of microwave ablation (MWA) combined with osteoplasty in lung cancer patients with painful extraspinal bone metastases. Materials and methods From January 2011 to July 2014, 26 lung cancer patients with 33 painful extraspinal bone metastases underwent percutaneous MWA combined with osteoplasty. Effectiveness was evaluated by visual analog scale (VAS) and daily morphine dose with a follow-up of 6-months. Complications were also recorded. Results Mean VAS score and morphine dose pre-procedure were 7.4 ± 1.6 (range, 5–10) and 47.7 ± 30.1 mg (range, 20–120 mg), respectively. Technical success and pain relief were achieved in all patients. Mean VAS scores and daily morphine doses post-procedure were as follows: 48 h, 1.7 ± 1.2 ( p