Recanalization therapies in acute ischemic stroke patients: impact of prior treatment with novel oral anticoagulants on bleeding complications and outcome

We explored the safety of intravenous thrombolysis (IVT) or intra-arterial treatment (IAT) in patients with ischemic stroke on non-vitamin K antagonist oral anticoagulants (NOACs, last intake

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2015-09, Vol.132 (13), p.1261-1269
Main Authors: Seiffge, David J, Hooff, Robbert-JanVan, Nolte, Christian H, Béjot, Yannick, Turc, Guillaume, Ikenberg, Benno, Berge, Eivind, Persike, Malte, Dequatre-Ponchelle, Nelly, Strbian, Daniel, Pfeilschifter, Waltraud, Zini, Andrea, Tveiten, Arnstein, Næss, Halvor, Michel, Patrik, Sztajzel, Roman, Luft, Andreas, Gensicke, Henrik, Traenka, Christopher, Hert, Lisa, Scheitz, Jan F, De Marchis, Gian Marco, Bonati, Leo H, Peters, Nils, Charidimou, Andreas, Werring, David J, Palm, Frederick, Reinhard, Matthias, Niesen, Wolf-Dirk, Nagao, Takehiko, Pezzini, Alessandro, Caso, Valeria, Nederkoorn, Paul J, Kägi, Georg, von Hessling, Alexander, Padjen, Visnja, Cordonnier, Charlotte, Erdur, Hebun, Lyrer, Philippe A, Brouns, Raf, Steiner, Thorsten, Tatlisumak, Turgut, Engelter, Stefan T
Format: Article
Language:English
Subjects:
Acute Disease
Administration, Oral
Aged
Aged, 80 and over
Anticoagulants - administration & dosage
Anticoagulants - adverse effects
Anticoagulants - classification
Anticoagulants - therapeutic use
Antithrombins - administration & dosage
Antithrombins - adverse effects
Antithrombins - therapeutic use
Atrial Fibrillation - complications
Brain Ischemia - blood
Brain Ischemia - drug therapy
Cerebral Hemorrhage - chemically induced
Cerebral Hemorrhage - epidemiology
Cohort Studies
Factor Xa Inhibitors - administration & dosage
Factor Xa Inhibitors - adverse effects
Factor Xa Inhibitors - therapeutic use
Female
Fibrinolytic Agents - therapeutic use
Humans
Incidence
Male
Middle Aged
Pilot Projects
Thrombolytic Therapy
Treatment Outcome
Vitamin K - antagonists & inhibitors
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Description
Summary:We explored the safety of intravenous thrombolysis (IVT) or intra-arterial treatment (IAT) in patients with ischemic stroke on non-vitamin K antagonist oral anticoagulants (NOACs, last intake
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.115.015484