Human African trypanosomiasis prevention, treatment and control costs: A systematic review

• Published in: Acta tropica 2015-10, Vol.150, p.4-13
• Main Authors: Keating, Joseph, Yukich, Joshua O., Sutherland, C. Simone, Woods, Geordie, Tediosi, Fabrizio
• Format: Article
• Language: English
• Subjects: Animals; Cattle; Control; Cost; Health Care Costs; Hospitalization - economics; Humans; Insect Control - economics; Prevention; Sleeping sickness; Treatment; Trypanosomiasis; Trypanosomiasis, African - drug therapy; Trypanosomiasis, African - prevention & control; Tsetse Flies
• ISSN: 0001-706X; 1873-6254
• DOI: 10.1016/j.actatropica.2015.06.003

Human African trypanosomiasis prevention, treatment and control costs: A systematic review. Keating J., Yukich J.O, Sutherland C.S., Woods G., Tediosi F. [Display omitted] •42 studies contained data on costs of prevention, treatment or control.•The literature available on HAT costs provides useful reference information.•Most of the literature is outdated and limited for estimating economic burden.•Updating HAT cost data could play a meaningful role in funding and advocacy The control and eventual elimination of human African trypanosomiasis (HAT) requires the expansion of current control and surveillance activities. A systematic review of the published literature on the costs of HAT prevention, treatment, and control, in addition to the economic burden, was conducted. All studies that contained primary or secondary data on costs of prevention, treatment and control were considered, resulting in the inclusion of 42 papers. The geographically focal nature of the disease and a lack of standardization in the cost data limit the usefulness of the available information for making generalizations across diverse settings. More recent information on the costs of treatment and control interventions for HAT is needed to provide accurate information for analyses and planning. The cost information contained herein can be used to inform rational decision making in control and elimination programs, and to assess potential synergies with existing vector-borne disease control programs, but programs would benefit significantly from new cost data collection.