Physio-chemical and antibacterial characteristics of pressure spun nylon nanofibres embedded with functional silver nanoparticles

• Published in: Materials Science & Engineering C 2015-11, Vol.56, p.195-204
• Main Authors: Xu, Z., Mahalingam, S., Rohn, J.L., Ren, G., Edirisinghe, M.
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Bacteria; Escherichia coli; Escherichia coli - growth & development; Fibers; Fibre; Fibres; Gyration; Metal Nanoparticles - chemistry; Nanofibers - chemistry; Nanofibres; Nanoparticles; Nanostructure; Nylons; Nylons - chemistry; Nylons - pharmacology; Particle Size; Polymer; Pressure; Pseudomonas aeruginosa; Pseudomonas aeruginosa - growth & development; Silver; Silver - chemistry; Silver - pharmacology
• ISSN: 0928-4931; 1873-0191
• DOI: 10.1016/j.msec.2015.06.003

A novel and facile approach to prepare hybrid nanoparticle embedded polymer nanofibers using pressurised gyration is presented. Silver nanoparticles and nylon polymer were used in this work. The polymer solution's physical properties, rotating speed and the working pressure had a significant influence on the fibre diameter and the morphology. Fibres in the range of 60–500nm were spun using 10wt.%, 15wt.% and 20wt.% nylon solutions and these bead-free fibres were processed under 0.2MPa and 0.3MPa working pressure and a rotational speed of 36,000rpm. 1–4wt.% of Ag was added to these nylon solutions and in the case of wt.% fibres in the range 50–150nm were prepared using the same conditions of pressurised gyration. Successful incorporation of the Ag nanoparticles in nylon nanofibres was confirmed by using a combination of advanced microscopical techniques and Raman spectrometry was used to study the bonding characteristics of nylon and the Ag nanoparticles. Inductively coupled plasma mass spectroscopy showed a substantial concentration of Ag ions in the nylon fibre matrix which is essential for producing effective antibacterial properties. Antibacterial activity of the Ag-loaded nanofibres shows higher efficacy than nylon nanofibres for Gram-negative Escherichia coli and Pseudomonas aeruginosa microorganisms, and both Ag nanoparticles and the Ag ions were found to be the reason for enhanced cell death in the bacterial solutions. [Display omitted] •Antibacterial nanoparticle embedded nanofibres were prepared by pressurised gyration.•Process parameters were able to effectively control fibre diameter and morphology.•Bonding between nanofibres and nanoparticles is explained using Raman spectroscopy.•Ag nanoparticle embedded nylon nanofibres show prolonged high antibacterial activity.