Evaluation of multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) for sulfur metabolic studies using super(34)S-labelled yeast

A multi-collector ICP-MS instrument was evaluated for the on-line measurement of sulfur isotope ratios during the liquid chromatographic separation of sulfur metabolites in mouse urine after the oral administration of super(34)S-labelled yeast. The multi-collector instrument used was equipped with b...

Full description

Saved in:
Bibliographic Details
Published in:Journal of analytical atomic spectrometry 2015-07, Vol.30 (8), p.1764-1773
Main Authors: San Blas, Oscar Galilea, Marchante Gayon, Juan Manuel, Garcia Alonso, Jose Ignacio
Format: Article
Language:English
Subjects:
Enrichment
Metabolites
Mice
Separation
Sulfur
Sulfur isotopes
Urine
Yeast
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A multi-collector ICP-MS instrument was evaluated for the on-line measurement of sulfur isotope ratios during the liquid chromatographic separation of sulfur metabolites in mouse urine after the oral administration of super(34)S-labelled yeast. The multi-collector instrument used was equipped with both Faraday cups and ion counters at positions L4 (32), C (33) and H4 (34). For the optimisation of the resolution, cup configuration and measurement conditions an artificial mixture of natural sulfur and highly enriched super(33)S and super(34)S was prepared. The results were compared with those obtained using a sector field single collector instrument from the same manufacturer. Both instruments provided good accuracy in the measurement of sulfur isotope ratios but better precision (
ISSN:0267-9477
1364-5544
DOI:10.1039/c4ja00383g