Correlates of Syncope in Patients With Acute Pulmonary Thromboembolism

Identification of pulmonary thromboembolism (PTE), as a cause of syncope, is important and may be life saving. We prospectively analyzed data on 335 patients with acute PTE. Relationships between syncope secondary to acute PTE and clinical findings, risk factors, and imaging modalities were analyzed...

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Published in:Clinical and applied thrombosis/hemostasis 2015-11, Vol.21 (8), p.772-776
Main Authors: Jenab, Yaser, Lotfi-Tokaldany, Masoumeh, Alemzadeh-Ansari, Mohammad-Javad, Seyyedi, Seyyed Reza, Shirani, Shapoor, Soudaee, Mehdi, Ghaffari-Marandi, Neda
Format: Article
Language:English
Subjects:
Acute Disease
Aged
Electrocardiography
Embolisms
Female
Health risk assessment
Humans
Male
Middle Aged
Prospective Studies
Pulmonary Embolism - complications
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - epidemiology
Pulmonary embolisms
Radiography
Syncope - diagnostic imaging
Syncope - epidemiology
Syncope - etiology
Thromboembolism
Ventricular Dysfunction, Right - diagnostic imaging
Ventricular Dysfunction, Right - epidemiology
Ventricular Dysfunction, Right - etiology
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Summary:Identification of pulmonary thromboembolism (PTE), as a cause of syncope, is important and may be life saving. We prospectively analyzed data on 335 patients with acute PTE. Relationships between syncope secondary to acute PTE and clinical findings, risk factors, and imaging modalities were analyzed. Of the 335 patients, 36 (10.7%) had syncope at presentation. Compared to patients without syncope, those with syncope had a higher frequency of right ventricular (RV) dysfunction (94.3% vs 72.1%, respectively; P value = .004) and saddle embolism (24.2% vs 10.9%, respectively; P value = .044). Frequency of RV dysfunction was similar between patients with and without saddle embolism. Although not significant, more patients with syncope had a history of previous PTE (P value = .086). By multivariable analysis, RV dysfunction and saddle embolism were independent correlates of syncope in patients with PTE. In-hospital mortality was not significantly different between the groups. In conclusion, among patients with PTE, RV dysfunction and saddle embolism were the independent correlates of syncope.
ISSN:1076-0296
1938-2723
DOI:10.1177/1076029614540037