Structure–activity relationships of natural and synthetic neo-clerodane diterpenes from Teucrium against Colorado potato beetle larvae

Treatment of potato leaf disks with ten neo-clerodane diterpenes isolated from Teucrium and with ten of their synthetic derivatives, resulted in a significant antifeedant activity against Leptinotarsa decemlineata larvae in both choice and no-choice assays for nine of the natural products and three...

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Bibliographic Details
Published in:Phytochemistry (Oxford) 1999-03, Vol.50 (5), p.749-753
Main Authors: López-Olguín, Jesús, de la Torre, María C, Ortego, Félix, Castañera, Pedro, Rodríguez, Benjamín
Format: Article
Language:English
Subjects:
Antifeedents
Biological and medical sciences
Chemical control
Chrysomelidae
Colorado potato beetle
Control
Fundamental and applied biological sciences. Psychology
Labiatea
Leptinotarsa decemlineata
Neo-clerodane diterpense
Phytopathology. Animal pests. Plant and forest protection
Protozoa. Invertebrates
Teucrium
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Summary:Treatment of potato leaf disks with ten neo-clerodane diterpenes isolated from Teucrium and with ten of their synthetic derivatives, resulted in a significant antifeedant activity against Leptinotarsa decemlineata larvae in both choice and no-choice assays for nine of the natural products and three of the hemisynthetic compounds. Changes in the antifeedant activity were associated with certain structural features of the compounds and some significant aspects of the structure–activity relationship are discussed.
ISSN:0031-9422
1873-3700
DOI:10.1016/S0031-9422(98)00642-6