Second chances

Abstract An 81-year-old woman presented with light perception vision in her left eye and had pallid swelling of the left optic disk. Temporal artery biopsy was normal. Magnetic resonance imaging revealed enlargement and enhancement of the left orbital optic nerve. There were vitreous cells, but a vi...

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Bibliographic Details
Published in:Survey of ophthalmology 2015-11, Vol.60 (6), p.596-599
Main Authors: Nagia, Lina, DO, Doyle, Jennifer I., MD, Hackney, James R., MD, Vaphiades, Michael S., DO, Kline, Lanning B., MD, Levin, Marc H., MD, PhD
Format: Article
Language:English
Subjects:
Aged, 80 and over
Astrocytoma - diagnosis
Astrocytoma - metabolism
Biomarkers, Tumor - metabolism
Female
Humans
Hypertrophy
IDH1 marker
Isocitrate Dehydrogenase - metabolism
Magnetic Resonance Imaging
Ophthalmology
Optic Nerve - pathology
optic nerve biopsy
optic nerve glioma/astrocytoma
Optic Nerve Neoplasms - diagnosis
Optic Nerve Neoplasms - metabolism
Papilledema - diagnosis
TP53 marker
Tumor Suppressor Protein p53 - metabolism
Vision Disorders - diagnosis
WHO grade II
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Summary:Abstract An 81-year-old woman presented with light perception vision in her left eye and had pallid swelling of the left optic disk. Temporal artery biopsy was normal. Magnetic resonance imaging revealed enlargement and enhancement of the left orbital optic nerve. There were vitreous cells, but a vitrectomy specimen showed only a benign lymphocytic population. Her vision deteriorated to no light perception in the left eye, and an optic nerve biopsy revealed a diffuse astrocytoma of World Health Organization grade II.
ISSN:0039-6257
1879-3304
DOI:10.1016/j.survophthal.2015.06.002