Naturally Occurring β-Nicotinamide Adenine Dinucleotide–Independent Avibacterium paragallinarum Isolate in Peru

The β-nicotinamide adenine dinucleotide (NAD) requirement has been considered to be essential for the isolation of the causal agent of infectious coryza, Avibacterium paragallinarum. Nevertheless, NAD-independent reports from South Africa and Mexico dismissed this paradigm. It is now accepted that b...

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Bibliographic Details
Published in:Avian diseases 2015-06, Vol.59 (2), p.341-343
Main Authors: Falconi-Agapito, Francesca, Saravia, Luis E, Flores-Pérez, Aldo, Fernández-Díaz, Manolo
Format: Article
Language:English
Subjects:
Animals
Avibacterium paragallinarum
Case Reports
Chickens
NAD - metabolism
NAD-independent
Pasteurellaceae
Pasteurellaceae Infections - epidemiology
Pasteurellaceae Infections - microbiology
Pasteurellaceae Infections - veterinary
Peru - epidemiology
Poultry Diseases - epidemiology
Poultry Diseases - microbiology
Respiratory Tract Diseases - epidemiology
Respiratory Tract Diseases - microbiology
Respiratory Tract Diseases - veterinary
V-factor
β-nicotinamide adenine dinucleotide (NAD)
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Summary:The β-nicotinamide adenine dinucleotide (NAD) requirement has been considered to be essential for the isolation of the causal agent of infectious coryza, Avibacterium paragallinarum. Nevertheless, NAD-independent reports from South Africa and Mexico dismissed this paradigm. It is now accepted that both NAD-dependent and NAD-independent agents are able to cause infectious coryza and thus belong to the species A. paragallinarum. Here, we report for the first time in Peru a NAD-independent isolate from broiler chickens with typical signs of infectious coryza that have received a trivalent inactivated vaccine against infectious coryza. The isolate was identified based on its morphology, biochemical and serologic tests, and PCR results. Partial 16S rRNA gene sequence analysis confirmed the isolate as A. paragallinarum. There have been no cases of NAD-independent A. paragallinarum isolates reported in South America. Increasing reports around the world highlight not only the need to reconsider the in vitro nutritional requirements of this species for its correct isolation but also the cross-protection conferred by commercial infectious coryza vaccines against NAD-independent isolates.
ISSN:0005-2086
1938-4351
1938-4351
DOI:10.1637/10969-110314-CaseR