Microbial screening for the enantiospecific production of alkyl esters of 4-chloro-3-hydroxybutanoic acid

This article describes our preliminary screening results of yeasts and fungi isolated from exotic environments like the Atlantic rain forest, from the roots of Araucaria angustifolia and from a Guava tree. Rhodotorula glutinis CCT 2182 and Cunninghamella echinulata CCT 4259 revealed high enantiosele...

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Bibliographic Details
Published in:Chemosphere (Oxford) 1999-04, Vol.38 (10), p.2243-2246
Main Authors: Cagnon, J.R., Marsaioli, A.J., Rialto, V.B., Pilli, R.A., Manflo, G.P., Eguchi, S.Y.
Format: Article
Language:English
Subjects:
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
butyric acid
Cunninghamella
Cunninghamella echinulata
enantiomers
enzyme activity
esters
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
organochlorine compounds
oxidoreductases
Rhodotorula glutinis
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Summary:This article describes our preliminary screening results of yeasts and fungi isolated from exotic environments like the Atlantic rain forest, from the roots of Araucaria angustifolia and from a Guava tree. Rhodotorula glutinis CCT 2182 and Cunninghamella echinulata CCT 4259 revealed high enantioselective reductase activities for the production of alkyl esters of (R)- and (S)-4-chloro-3-hydroxybutanoic acid, respectively.
ISSN:0045-6535
1879-1298
DOI:10.1016/S0045-6535(98)00443-3