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Curacin D, aN antimitotic agent from the marine Cyanobacterium Lyngbya majuscula
Curacin D is a novel brine shrimp toxic metabolite isolated from a Virgin Islands collection of the marine cyanobacterium Lyngbya majuscula. Structure elucidation of curacin D was accomplished through multidimensional NMR, GC/MS, and comparisons with curacin A. Curacin D provides new insights into s...
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| Published in: | Phytochemistry (Oxford) 1998-12, Vol.49 (8), p.2387-2389 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c510t-2c76df27e7d0473e954bc135b5b9ef883b4560ffa52f8abce1bbc0c097a710733 |
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| cites | cdi_FETCH-LOGICAL-c510t-2c76df27e7d0473e954bc135b5b9ef883b4560ffa52f8abce1bbc0c097a710733 |
| container_end_page | 2389 |
| container_issue | 8 |
| container_start_page | 2387 |
| container_title | Phytochemistry (Oxford) |
| container_volume | 49 |
| creator | Márquez, Brian Verdier-Pinard, Pascal Hamel, Ernest Gerwick, William H. |
| description | Curacin D is a novel brine shrimp toxic metabolite isolated from a Virgin Islands collection of the marine cyanobacterium
Lyngbya majuscula. Structure elucidation of curacin D was accomplished through multidimensional NMR, GC/MS, and comparisons with curacin A. Curacin D provides new insights into structure–activity relationships in this natural product class as well as some aspects of the likely biosynthetic pathway of the curacins. |
| doi_str_mv | 10.1016/S0031-9422(98)00365-3 |
| format | article |
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Lyngbya majuscula. Structure elucidation of curacin D was accomplished through multidimensional NMR, GC/MS, and comparisons with curacin A. 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| ispartof | Phytochemistry (Oxford), 1998-12, Vol.49 (8), p.2387-2389 |
| issn | 0031-9422 1873-3700 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_17252026 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | antiproliferative Artemia salina biochemical pathways Biological and medical sciences blue–green alga chemical composition chemical structure cyanobacteria Cyanobacteria - chemistry General pharmacology Humans Lyngbya Lyngbya majuscula Lyngbya majuscula: Oscillatoriaceae Magnetic Resonance Spectroscopy Marine Mass Spectrometry Medical sciences mitosis Mitosis - drug effects Molecular Structure nuclear magnetic resonance spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments secondary metabolites spectral analysis structure-activity relationships Thiazoles - chemistry Thiazoles - isolation & purification thiazoline alkaloid toxicity Tumor Cells, Cultured |
| title | Curacin D, aN antimitotic agent from the marine Cyanobacterium Lyngbya majuscula |
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