Selection of drug-resistant HIV

Resistance to antiretroviral drugs by HIV develops from competition among several different virus variants within an individual. Recent studies have measured the changing proportions of HIV populations, which differ by single nucleic acids, under the selective pressures exerted by the addition or re...

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Bibliographic Details
Published in:Trends in Microbiology 1999-03, Vol.7 (3), p.120-123
Main Authors: Harrigan, P.Richard, Alexander, Christopher S.
Format: Article
Language:English
Subjects:
Animals
antiretroviral drugs
drug resistance
Drug Resistance, Microbial
evolution
HIV
HIV-1 - drug effects
HIV-1 - genetics
Human immunodeficiency virus
Humans
Mutagenesis
Retrovirus
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Summary:Resistance to antiretroviral drugs by HIV develops from competition among several different virus variants within an individual. Recent studies have measured the changing proportions of HIV populations, which differ by single nucleic acids, under the selective pressures exerted by the addition or removal of antiretroviral drugs.
ISSN:0966-842X
1878-4380
DOI:10.1016/S0966-842X(99)01467-5