Circulating IL-33 level is associated with the progression of lung cancer

Highlights • Plasma levels of IL-33 increased in the early stage of lung cancer. • The levels decreased in accordance with the progression. • Surgical removal of the lung cancer also decreased the level. • IL-33 protein was expressed by the normal bronchial epithelium and vascular endothelium....

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Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2015-11, Vol.90 (2), p.346-351
Main Authors: Kim, Myung Shin, Kim, Eunsom, Heo, Jeong-Seok, Bae, Da-Jeong, Lee, Jong-Uk Wook, Lee, Tae-Hyeong, Lee, Hyeon Ju, Chang, Hun Soo, Park, Jong Sook, Jang, An Soo, Koh, Eun Suk, Hwang, Hun Gyu, Lim, Guneil, Kim, Soohyun, Park, Choon-Sik
Format: Article
Language:English
Subjects:
Aged
Case-Control Studies
Chemotherapy
Disease Progression
Female
Hematology, Oncology and Palliative Medicine
Humans
Interleukin-33
Interleukin-33 - blood
Lung - pathology
Lung cancer
Lung Neoplasms - blood
Lung Neoplasms - pathology
Male
Middle Aged
Neoplasm Staging - methods
Plasma
Pneumonectomy - methods
Pulmonary/Respiratory
Stage
Surgery
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Summary:Highlights • Plasma levels of IL-33 increased in the early stage of lung cancer. • The levels decreased in accordance with the progression. • Surgical removal of the lung cancer also decreased the level. • IL-33 protein was expressed by the normal bronchial epithelium and vascular endothelium.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2015.08.011