Folliculotropic Mycosis Fungoides as a Posttransplant Lymphoproliferative Disorder

Posttransplant lymphoproliferative disorder (PTLD) is a known complication of solid organ transplantation. The majority are B cell in origin and related to Epstein-Barr virus infection. T-cell PTLD is much less common; most are Epstein-Barr virus negative and have a worse prognosis. Primary cutaneou...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 2015-09, Vol.136 (3), p.e701-e705
Main Authors: Spence-Shishido, Allyson, Streicher, Jenna L, George, Roshan P, Parker, Sareeta R, Lawley, Leslie P
Format: Article
Language:English
Subjects:
Adolescent
Care and treatment
Company business management
Cutaneous T cell lymphoma
Epstein-Barr virus
Humans
Immunocompromised Host
Immunosuppressive Agents - adverse effects
Influence
Kidney Transplantation - adverse effects
Lymphoma
Male
Management
Medical prognosis
Mycosis fungoides
Mycosis Fungoides - etiology
Mycosis Fungoides - therapy
Patients
Pediatrics
Skin Neoplasms - etiology
Skin Neoplasms - therapy
T cell receptors
Transplants & implants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Posttransplant lymphoproliferative disorder (PTLD) is a known complication of solid organ transplantation. The majority are B cell in origin and related to Epstein-Barr virus infection. T-cell PTLD is much less common; most are Epstein-Barr virus negative and have a worse prognosis. Primary cutaneous T-cell lymphoma (CTCL) as a presentation of PTLD is rare. CTCL has a less favorable prognosis in transplant patients compared with that in immune-competent patients. Herein, we report a case of a 13-year-old boy who developed folliculotropic mycosis fungoides, a rare subtype of CTCL, subsequent to renal transplantation. To our knowledge, this is the first report of this type of PTLD in a pediatric patient.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2014-3787