Loading…

Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist

Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. • Nutritional counselling may be beneficial in delaying cachexia. • Anamorelin is a first-in-class, orally active ghrelin receptor agonist....

Full description

Saved in:
Bibliographic Details
Published in:Cancer treatment reviews 2015-11, Vol.41 (9), p.793-797
Main Authors: Esposito, Angela, Criscitiello, Carmen, Gelao, Lucia, Pravettoni, Gabriella, Locatelli, Marzia, Minchella, Ida, Di Leo, Maria, Liuzzi, Rita, Milani, Alessandra, Massaro, Mariangela, Curigliano, Giuseppe
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783
cites cdi_FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783
container_end_page 797
container_issue 9
container_start_page 793
container_title Cancer treatment reviews
container_volume 41
creator Esposito, Angela
Criscitiello, Carmen
Gelao, Lucia
Pravettoni, Gabriella
Locatelli, Marzia
Minchella, Ida
Di Leo, Maria
Liuzzi, Rita
Milani, Alessandra
Massaro, Mariangela
Curigliano, Giuseppe
description Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. • Nutritional counselling may be beneficial in delaying cachexia. • Anamorelin is a first-in-class, orally active ghrelin receptor agonist.
doi_str_mv 10.1016/j.ctrv.2015.09.002
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1727989277</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0305737215001668</els_id><sourcerecordid>1727989277</sourcerecordid><originalsourceid>FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783</originalsourceid><addsrcrecordid>eNp9kc1u1DAUhS1ERaeFF2CBvGST4J_ajiWEhCooSK26ANaWY990PCTxYHsGZtd34A15EhxNYcECb2zJ556r8x2EnlPSUkLlq03rStq3jFDREt0Swh6hFRWcNVRL9RitCCeiUVyxU3SW84YQornUT9Apk7yTuhMrNN2AW9s55CnjOGA7xwQ_gv11_9NZt16eOB9mn-IE9dPjZEuIsx3xEBMuCWyZYC74eyhrnGEEV8Ie8N06wRhmnMDBtlSlvYt1R3mKTgY7Znj2cJ-jL-_ffb780FzfXn28fHvduAtKSwOCuprAK2e9Bs65FtL3euiZkGoQjisvB6usV1rU40VHoeuZGy5I33vV8XP08ui7TfHbDnIxU8gOxtHOEHfZUMWU7jRTqkrZUepSzDnBYLYpTDYdDCVmwWw2ZsFsFsyGaFMx16EXD_67fgL_d-QP1yp4fRRATbkPkEx2AWYHPlQmxfgY_u__5p9xV3EGZ8evcIC8ibtUO6g5TGaGmE9L0UvPVJDqKDv-G3N0pyU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1727989277</pqid></control><display><type>article</type><title>Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Esposito, Angela ; Criscitiello, Carmen ; Gelao, Lucia ; Pravettoni, Gabriella ; Locatelli, Marzia ; Minchella, Ida ; Di Leo, Maria ; Liuzzi, Rita ; Milani, Alessandra ; Massaro, Mariangela ; Curigliano, Giuseppe</creator><creatorcontrib>Esposito, Angela ; Criscitiello, Carmen ; Gelao, Lucia ; Pravettoni, Gabriella ; Locatelli, Marzia ; Minchella, Ida ; Di Leo, Maria ; Liuzzi, Rita ; Milani, Alessandra ; Massaro, Mariangela ; Curigliano, Giuseppe</creatorcontrib><description>Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. • Nutritional counselling may be beneficial in delaying cachexia. • Anamorelin is a first-in-class, orally active ghrelin receptor agonist.</description><identifier>ISSN: 0305-7372</identifier><identifier>EISSN: 1532-1967</identifier><identifier>DOI: 10.1016/j.ctrv.2015.09.002</identifier><identifier>PMID: 26386985</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Anamorelin ; Animals ; Anorexia - drug therapy ; Anorexia - etiology ; Anorexia - metabolism ; Cachexia - drug therapy ; Cachexia - etiology ; Cachexia - metabolism ; Cancer cachexia ; Ghrelin receptor ; Hematology, Oncology and Palliative Medicine ; Humans ; Hydrazines - pharmacology ; Hydrazines - therapeutic use ; Neoplasms - complications ; Neoplasms - metabolism ; Oligopeptides - pharmacology ; Oligopeptides - therapeutic use ; Receptors, Ghrelin - agonists ; Receptors, Ghrelin - metabolism ; Syndrome</subject><ispartof>Cancer treatment reviews, 2015-11, Vol.41 (9), p.793-797</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783</citedby><cites>FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26386985$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Esposito, Angela</creatorcontrib><creatorcontrib>Criscitiello, Carmen</creatorcontrib><creatorcontrib>Gelao, Lucia</creatorcontrib><creatorcontrib>Pravettoni, Gabriella</creatorcontrib><creatorcontrib>Locatelli, Marzia</creatorcontrib><creatorcontrib>Minchella, Ida</creatorcontrib><creatorcontrib>Di Leo, Maria</creatorcontrib><creatorcontrib>Liuzzi, Rita</creatorcontrib><creatorcontrib>Milani, Alessandra</creatorcontrib><creatorcontrib>Massaro, Mariangela</creatorcontrib><creatorcontrib>Curigliano, Giuseppe</creatorcontrib><title>Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist</title><title>Cancer treatment reviews</title><addtitle>Cancer Treat Rev</addtitle><description>Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. • Nutritional counselling may be beneficial in delaying cachexia. • Anamorelin is a first-in-class, orally active ghrelin receptor agonist.</description><subject>Anamorelin</subject><subject>Animals</subject><subject>Anorexia - drug therapy</subject><subject>Anorexia - etiology</subject><subject>Anorexia - metabolism</subject><subject>Cachexia - drug therapy</subject><subject>Cachexia - etiology</subject><subject>Cachexia - metabolism</subject><subject>Cancer cachexia</subject><subject>Ghrelin receptor</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Hydrazines - pharmacology</subject><subject>Hydrazines - therapeutic use</subject><subject>Neoplasms - complications</subject><subject>Neoplasms - metabolism</subject><subject>Oligopeptides - pharmacology</subject><subject>Oligopeptides - therapeutic use</subject><subject>Receptors, Ghrelin - agonists</subject><subject>Receptors, Ghrelin - metabolism</subject><subject>Syndrome</subject><issn>0305-7372</issn><issn>1532-1967</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1DAUhS1ERaeFF2CBvGST4J_ajiWEhCooSK26ANaWY990PCTxYHsGZtd34A15EhxNYcECb2zJ556r8x2EnlPSUkLlq03rStq3jFDREt0Swh6hFRWcNVRL9RitCCeiUVyxU3SW84YQornUT9Apk7yTuhMrNN2AW9s55CnjOGA7xwQ_gv11_9NZt16eOB9mn-IE9dPjZEuIsx3xEBMuCWyZYC74eyhrnGEEV8Ie8N06wRhmnMDBtlSlvYt1R3mKTgY7Znj2cJ-jL-_ffb780FzfXn28fHvduAtKSwOCuprAK2e9Bs65FtL3euiZkGoQjisvB6usV1rU40VHoeuZGy5I33vV8XP08ui7TfHbDnIxU8gOxtHOEHfZUMWU7jRTqkrZUepSzDnBYLYpTDYdDCVmwWw2ZsFsFsyGaFMx16EXD_67fgL_d-QP1yp4fRRATbkPkEx2AWYHPlQmxfgY_u__5p9xV3EGZ8evcIC8ibtUO6g5TGaGmE9L0UvPVJDqKDv-G3N0pyU</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>Esposito, Angela</creator><creator>Criscitiello, Carmen</creator><creator>Gelao, Lucia</creator><creator>Pravettoni, Gabriella</creator><creator>Locatelli, Marzia</creator><creator>Minchella, Ida</creator><creator>Di Leo, Maria</creator><creator>Liuzzi, Rita</creator><creator>Milani, Alessandra</creator><creator>Massaro, Mariangela</creator><creator>Curigliano, Giuseppe</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151101</creationdate><title>Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist</title><author>Esposito, Angela ; Criscitiello, Carmen ; Gelao, Lucia ; Pravettoni, Gabriella ; Locatelli, Marzia ; Minchella, Ida ; Di Leo, Maria ; Liuzzi, Rita ; Milani, Alessandra ; Massaro, Mariangela ; Curigliano, Giuseppe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Anamorelin</topic><topic>Animals</topic><topic>Anorexia - drug therapy</topic><topic>Anorexia - etiology</topic><topic>Anorexia - metabolism</topic><topic>Cachexia - drug therapy</topic><topic>Cachexia - etiology</topic><topic>Cachexia - metabolism</topic><topic>Cancer cachexia</topic><topic>Ghrelin receptor</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Hydrazines - pharmacology</topic><topic>Hydrazines - therapeutic use</topic><topic>Neoplasms - complications</topic><topic>Neoplasms - metabolism</topic><topic>Oligopeptides - pharmacology</topic><topic>Oligopeptides - therapeutic use</topic><topic>Receptors, Ghrelin - agonists</topic><topic>Receptors, Ghrelin - metabolism</topic><topic>Syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Esposito, Angela</creatorcontrib><creatorcontrib>Criscitiello, Carmen</creatorcontrib><creatorcontrib>Gelao, Lucia</creatorcontrib><creatorcontrib>Pravettoni, Gabriella</creatorcontrib><creatorcontrib>Locatelli, Marzia</creatorcontrib><creatorcontrib>Minchella, Ida</creatorcontrib><creatorcontrib>Di Leo, Maria</creatorcontrib><creatorcontrib>Liuzzi, Rita</creatorcontrib><creatorcontrib>Milani, Alessandra</creatorcontrib><creatorcontrib>Massaro, Mariangela</creatorcontrib><creatorcontrib>Curigliano, Giuseppe</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer treatment reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Esposito, Angela</au><au>Criscitiello, Carmen</au><au>Gelao, Lucia</au><au>Pravettoni, Gabriella</au><au>Locatelli, Marzia</au><au>Minchella, Ida</au><au>Di Leo, Maria</au><au>Liuzzi, Rita</au><au>Milani, Alessandra</au><au>Massaro, Mariangela</au><au>Curigliano, Giuseppe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist</atitle><jtitle>Cancer treatment reviews</jtitle><addtitle>Cancer Treat Rev</addtitle><date>2015-11-01</date><risdate>2015</risdate><volume>41</volume><issue>9</issue><spage>793</spage><epage>797</epage><pages>793-797</pages><issn>0305-7372</issn><eissn>1532-1967</eissn><abstract>Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. • Nutritional counselling may be beneficial in delaying cachexia. • Anamorelin is a first-in-class, orally active ghrelin receptor agonist.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>26386985</pmid><doi>10.1016/j.ctrv.2015.09.002</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0305-7372
ispartof Cancer treatment reviews, 2015-11, Vol.41 (9), p.793-797
issn 0305-7372
1532-1967
language eng
recordid cdi_proquest_miscellaneous_1727989277
source ScienceDirect Freedom Collection 2022-2024
subjects Anamorelin
Animals
Anorexia - drug therapy
Anorexia - etiology
Anorexia - metabolism
Cachexia - drug therapy
Cachexia - etiology
Cachexia - metabolism
Cancer cachexia
Ghrelin receptor
Hematology, Oncology and Palliative Medicine
Humans
Hydrazines - pharmacology
Hydrazines - therapeutic use
Neoplasms - complications
Neoplasms - metabolism
Oligopeptides - pharmacology
Oligopeptides - therapeutic use
Receptors, Ghrelin - agonists
Receptors, Ghrelin - metabolism
Syndrome
title Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T23%3A36%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mechanisms%20of%20anorexia%E2%80%93cachexia%20syndrome%20and%20rational%20for%20treatment%20with%20selective%20ghrelin%20receptor%20agonist&rft.jtitle=Cancer%20treatment%20reviews&rft.au=Esposito,%20Angela&rft.date=2015-11-01&rft.volume=41&rft.issue=9&rft.spage=793&rft.epage=797&rft.pages=793-797&rft.issn=0305-7372&rft.eissn=1532-1967&rft_id=info:doi/10.1016/j.ctrv.2015.09.002&rft_dat=%3Cproquest_cross%3E1727989277%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c411t-e51c967d7cad9e333956db9fb2567f5c37d6fa7ad795555d581e8b2cf40bbd783%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1727989277&rft_id=info:pmid/26386985&rfr_iscdi=true