Acute responses to exercise training and relationship with exercise adherence in moderate chronic obstructive pulmonary disease

• Published in: Chronic respiratory disease 2015-11, Vol.12 (4), p.329-339
• Main Authors: Rizk, Amanda K, Wardini, Rima, Chan-Thim, Emilie, Bacon, Simon L, Lavoie, Kim L, Pepin, Véronique
• Format: Article
• Language: English
• Subjects: Affect; Aged; Exercise - physiology; Exercise - psychology; Exercise Therapy - methods; Female; Forced Expiratory Volume; Heart Rate; Humans; Linear Models; Male; Middle Aged; Oximetry; Patient Compliance - psychology; Patient Compliance - statistics & numerical data; Pulmonary Disease, Chronic Obstructive - physiopathology; Pulmonary Disease, Chronic Obstructive - rehabilitation; Pulmonary Ventilation; Respiratory Rate; Severity of Illness Index; Tidal Volume
• ISSN: 1479-9723; 1479-9731; 1479-9731
• DOI: 10.1177/1479972315598691

The objectives of our study were to (i) compare, in chronic obstructive pulmonary disease (COPD) patients, acute responses to continuous training at high intensity (CTHI), continuous training at ventilatory threshold (CTVT) and interval training (IT); (ii) examine associations between acute responses and 12-week adherence; and (iii) investigate whether the relationship between acute responses and adherence is mediated/moderated by affect/vigour. Thirty-five COPD patients (forced expiratory volume in 1 second = 60.2 ± 15.8% predicted), underwent baseline assessments, were randomly assigned to CTHI, CTVT or IT, were monitored throughout about before training, and underwent 12 weeks of exercise training during which adherence was tracked. Compared with CTHI, CTVT was associated with lower respiratory exchange ratio, heart rate and respiratory rate (RR), while IT induced higher V ̇ E , V ̇ E / maximal voluntary ventilation, RR and lower pulse oxygen saturation. From pre- to post-exercise, positive affect increased (F = 9.74, p < 0.001) and negative affect decreased (F = 6.43, p = 0.005) across groups. CTVT reported greater end-exercise vigour compared to CTHI (p = 0.01) and IT (p = 0.02). IT exhibited lowest post-exercise vigour (p = 0.04 versus CTHI, p = 0.02 versus CTVT) and adherence rate (F = 6.69, p = 0.004). Mean V ̇ O 2 (r = −0.466, p = 0.007) and end-exercise vigour (r = 0.420, p = 0.017) were most strongly correlated with adherence. End-exercise vigour moderated the relationship between V ̇ O 2 and adherence (β = 2.74, t(32) = 2.32, p = 0.03). In summary, CTHI, CTVT and IT improved affective valence from rest to post-exercise and induced a significant 12-week exercise training effect. However, they elicited different acute physiological responses, which in turn were associated with differences in 12-week adherence to the target training intensity. This association was moderated by acute end-exercise vigour.