Alternate current biosusceptometry for the assessment of gastric motility after proximal gastrectomy in rats: a feasibility study

Background This study proposes an experimental model to assess the consequences of gastric surgeries on gastric motility. We investigated the effects of proximal gastrectomy (PG) using a non‐invasive technique (alternate current biosusceptometry [ACB]) on gastric contractility (GC), gastric emptying...

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Published in:Neurogastroenterology and motility 2015-11, Vol.27 (11), p.1613-1620
Main Authors: Calabresi, M. F. F., Quini, C. C., Matos, J. F., Moretto, G. M., Americo, M. F., Graça, J. R. V., Santos, A. A., Oliveira, R. B., Pina, D. R., Miranda, J. R. A.
Format: Article
Language:English
Subjects:
AC Biosusceptometry
Animals
Feasibility Studies
Gastrectomy - adverse effects
gastric contractility
gastric emptying
gastric motility
Gastrointestinal Motility - physiology
Magnetic Phenomena
Male
Models, Animal
proximal gastrectomy
Rats
Rats, Wistar
Stomach - surgery
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Summary:Background This study proposes an experimental model to assess the consequences of gastric surgeries on gastric motility. We investigated the effects of proximal gastrectomy (PG) using a non‐invasive technique (alternate current biosusceptometry [ACB]) on gastric contractility (GC), gastric emptying (GE), and orocecal transit (OCT) after the ingestion of liquids and solids in rats. Methods Twenty‐four male rats were subjected to gastric motility assessment before and after the PG procedure. The GE and OCT results are expressed as the mean time of gastric emptying (MGET) and cecum arrival (MCAT). The GC recordings are presented as the frequency and amplitude of contractions. Key Results Mean time of gastric emptying after solid meals were significantly different (p 
ISSN:1350-1925
1365-2982
DOI:10.1111/nmo.12660