Epidemiology of ductal carcinoma in situ in Western Australia: implications for surgical margins and management

Background In 2010, the Australian Institute of Health and Welfare published a report examining the characteristics of Australian women diagnosed with ductal carcinoma in situ (DCIS). This study identified the characteristics of women who were diagnosed with DCIS in Western Australia (WA) 1996–2005,...

Full description

Saved in:
Bibliographic Details
Published in:Breast cancer (Tokyo, Japan) Japan), 2015-11, Vol.22 (6), p.641-647
Main Authors: Butler-Henderson, Kerryn, Lee, Andy H., Lenzo, Nat P., Price, Roger I.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Analysis
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Cancer
Cancer Research
Carcinoma, Ductal
Carcinoma, Intraductal, Noninfiltrating - epidemiology
Carcinoma, Intraductal, Noninfiltrating - pathology
Carcinoma, Intraductal, Noninfiltrating - surgery
Epidemiology
Female
Health aspects
Humans
Kaplan-Meier Estimate
Lumpectomy
Mastectomy, Segmental - statistics & numerical data
Medicine
Medicine & Public Health
Middle Aged
Oncology
Oncology, Experimental
Original Article
Radiotherapy
Registries
Risk Factors
Surgery
Surgical Oncology
Survival Rate
Western Australia - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background In 2010, the Australian Institute of Health and Welfare published a report examining the characteristics of Australian women diagnosed with ductal carcinoma in situ (DCIS). This study identified the characteristics of women who were diagnosed with DCIS in Western Australia (WA) 1996–2005, and built on a national study by determining the rate of second operation and breast cancer events (BCE) in WA. Methods A retrospective analysis of data from the WA Cancer Registry and the Hospital Morbidity Database was undertaken. The main outcome measures were histological characteristics, second operation rate, breast cancer events. Results A total of 1356 cases of DCIS were diagnosed in WA between 1996 and 2005, with a minimum 5-year follow-up. The age-standardised incidence rate in 2005 was 15.4 per 100,000 women. 72 % of patients received breast-conserving therapy for primary treatment, 18 % of patients requiring a second operation to obtain adequate margins and 35 % of patients received postoperative radiotherapy. 17.3 % of cases had a subsequent BCE, with the 5- and 10-year probabilities being 4.36 and 8.27 %, respectively. A BCE was significantly associated with age ( p  
ISSN:1340-6868
1880-4233
DOI:10.1007/s12282-014-0531-5