Mobilization of Iron from Coal Fly Ash Was Dependent upon the Particle Size and the Source of Coal

Particulate air pollution, including coal fly ash, contains iron, and some of the pathological effects after inhalation may be due to reactive oxygen species produced by iron-catalyzed reactions. The objective of this study was to determine whether iron, present in coal fly ash, was mobilized, leadi...

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Bibliographic Details
Published in:Chemical research in toxicology 1998-12, Vol.11 (12), p.1494-1500
Main Authors: Smith, Kevin R, Veranth, John M, Lighty, JoAnn S, Aust, Ann E
Format: Article
Language:English
Subjects:
Air Pollutants, Occupational - analysis
Carbon - analysis
Citrates - chemistry
Coal - analysis
Coal Ash
Cytochalasin D - chemistry
Ferritins - analysis
Ferrozine - chemistry
Indicators and Reagents
Iron - chemistry
Mass Spectrometry
Particle Size
Particulate Matter
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Summary:Particulate air pollution, including coal fly ash, contains iron, and some of the pathological effects after inhalation may be due to reactive oxygen species produced by iron-catalyzed reactions. The objective of this study was to determine whether iron, present in coal fly ash, was mobilized, leading to ferritin induction in human airway epithelial cells, and whether the size of the particles affected the amount of iron mobilized. Three types of coal were used to generate the three size fractions of fly ash collected. The Utah coal fly ash was generated from a bituminous b coal, the Illinois coal fly ash from a bituminous c coal, and the North Dakota coal fly ash from a lignite a coal. Three size fractions were studied to compare the amount of iron mobilized in human airway epithelial (A549) cells and by citrate in cell-free suspensions. The size fractions selected were fine (
ISSN:0893-228X
1520-5010
DOI:10.1021/tx980142v