Zirconia with laser-modified microgrooved surface vs. titanium implants covered with melatonin stimulates bone formation. Experimental study in tibia rabbits

Objectives The aim of the study was to evaluate if zirconia implants with micro‐grooved surfaces supplemented with melatonin enhance the bone‐to‐implant contact (BIC) vs. titanium implants with the same coating. Materials and methods Eighty implants divided in four groups were inserted in the tibia...

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Bibliographic Details
Published in:Clinical oral implants research 2015-12, Vol.26 (12), p.1421-1429
Main Authors: Calvo-Guirado, José Luis, Aguilar Salvatierra, Antonio, Gargallo-Albiol, Jordi, Delgado-Ruiz, Rafael Arcesio, Maté Sanchez, Jose Eduardo, Satorres-Nieto, Marta
Format: Article
Language:English
Subjects:
Animals
Bone growth
Bone implants
bone-to-implant contact
Coated Materials, Biocompatible
Connective tissues
Dental Implantation, Endosseous - methods
Dental Implants
Dental Prosthesis Design
Dentistry
Implants, Experimental
Male
Melatonin
Melatonin - pharmacology
Microscopy, Electron, Scanning
Osteogenesis
Osteogenesis - drug effects
Pilot Projects
Rabbits
Surface Properties
Surgical implants
Tibia
Tibia - surgery
Titanium
titanium implants
Zirconia
zirconia implants
Zirconium
Zirconium dioxide
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Summary:Objectives The aim of the study was to evaluate if zirconia implants with micro‐grooved surfaces supplemented with melatonin enhance the bone‐to‐implant contact (BIC) vs. titanium implants with the same coating. Materials and methods Eighty implants divided in four groups were inserted in the tibia of 20 New Zealand rabbits as follows: (group A) 20 titanium implants; (group B) 20 micro‐grooved zirconia implants; (group C) 20 titanium implants supplemented with melatonin and (group D) 20 micro‐grooved zirconia implants supplemented with melatonin. Histometric and SEM evaluation of BIC were evaluated after 1 and 4 weeks. Results At 1 week, group C (29.7 ± 2.4%) and group D (28.9 ± 1.3%) implants showed higher BIC% compared with group A and B (P 
ISSN:0905-7161
1600-0501
DOI:10.1111/clr.12472