Practical synthesis of fingolimod from diethyl acetamidomalonate

A facile six-step synthesis of fingolimod, starting from readily available and inexpensive starting material diethyl acetamidomalonate, in very good yield is demonstrated.

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Bibliographic Details
Published in:RSC advances 2013-01, Vol.3 (25), p.9687-9689
Main Authors: Kandagatla, Bhaskar, Prasada Raju, Vetukuri Venkata Naga Kali Vara, Kumar, Narayana Sravan, Reddy, Ganta Madhusudhan, Srinivas, Katkam, Iqbal, Javed, Bandichhor, Rakeshwar, Oruganti, Srinivas
Format: Article
Language:English
Subjects:
Synthesis
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Description
Summary:A facile six-step synthesis of fingolimod, starting from readily available and inexpensive starting material diethyl acetamidomalonate, in very good yield is demonstrated.
ISSN:2046-2069
2046-2069
DOI:10.1039/c3ra40894a