Reversible photo-responsive vesicle based on the complexation between an azobenzene containing molecule and α-cyclodextrin

An amphiphilic molecule (Azo-Cl) was successfully synthesized and found to be able to construct reversible spherical vesicles in water. The assembled vesicles disappeared on the addition of equimolar α-cyclodextrin (α-CD) and reformed with UV irradiation due to the exclusion of the cis -azobenzene (...

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Bibliographic Details
Published in:RSC advances 2015-01, Vol.5 (41), p.32846-32852
Main Authors: Liu, Jianjia, Yan, Liang, Wang, Jie, Li, Tao, Zhao, Hanqing, Li, Li, Lincoln, Stephen F., Prud’homme, Robert K., Guo, Xuhong
Format: Article
Language:English
Subjects:
Azo
Biomimetics
Carriers
Carriers, Drug
Complexation
Holes
Irradiation
Vesicles
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Summary:An amphiphilic molecule (Azo-Cl) was successfully synthesized and found to be able to construct reversible spherical vesicles in water. The assembled vesicles disappeared on the addition of equimolar α-cyclodextrin (α-CD) and reformed with UV irradiation due to the exclusion of the cis -azobenzene (Azo) group from α-CD’s hydrophobic cavity. With Vis irradiation, the vesicles were demolished again as α-CD combined with the Azo group again. These reversible photo-responsive vesicles based on the complexation between Azo-Cl and α-CD should be ideal switchable biomimetic membranes or carriers for photo-controllable release of functional matters like drugs.
ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA04597E