Osteopenia Associated with Increased Prolactin and Aging in Psychiatric Patients Treated with Prolactin-Elevating Antipsychotics

: The aim of this study was to determine the prevalence of osteopenia in schizophrenic patients with hyperprolactinemia and to identify factors influencing bone density. Our results indicate that low bone mineral density was highly prevalent in a chronic psychiatric population treated with prolactin...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 2004-12, Vol.1032 (1), p.297-298
Main Authors: LIU-SEIFERT, HONG, KINON, BRUCE J., AHL, JONNA, LAMBERSON, SHAW
Format: Article
Language:English
Subjects:
Adult
Aging - physiology
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
bone density
Bone Density - drug effects
Bone Diseases, Metabolic - blood
Bone Diseases, Metabolic - chemically induced
Bone Diseases, Metabolic - epidemiology
fasting serum lipids
Female
Humans
Male
olanzapine
Osteoporosis - blood
Osteoporosis - chemically induced
Osteoporosis - epidemiology
Prolactin - blood
Risk Factors
Schizophrenia - blood
Schizophrenia - complications
Schizophrenia - drug therapy
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Summary:: The aim of this study was to determine the prevalence of osteopenia in schizophrenic patients with hyperprolactinemia and to identify factors influencing bone density. Our results indicate that low bone mineral density was highly prevalent in a chronic psychiatric population treated with prolactin‐elevating antipsychotics. Identified risk factors appear to be age and hyperprolactinemia for both females and males.
ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1314.044