Laparoscopic splenectomy for patients with liver cirrhosis: Improvement of liver function in patients with Child-Pugh class B

Background We aimed to assess the short-term outcomes of laparoscopic splenectomy (LS) and liver function at 1 year after splenectomy in the patients with liver cirrhosis. Methods Forty-five patients with liver cirrhosis and hypersplenism underwent LS. We reviewed electronic medical records regardin...

Full description

Saved in:
Bibliographic Details
Published in:Surgery 2015-12, Vol.158 (6), p.1538-1544
Main Authors: Yamamoto, Naoki, MD, Okano, Keiichi, MD, Oshima, Minoru, MD, Akamoto, Shitaro, MD, Fujiwara, Masao, MD, Tani, Joji, MD, Miyoshi, Hisaaki, MD, Yoneyama, Hirohito, MD, Masaki, Tsutomu, MD, Suzuki, Yasuyuki, MD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Carcinoma, Hepatocellular - epidemiology
Comorbidity
Esophageal and Gastric Varices - epidemiology
Female
Follow-Up Studies
Humans
Hypersplenism - surgery
Incidence
Laparoscopy - methods
Liver - physiology
Liver - surgery
Liver Cirrhosis - classification
Liver Cirrhosis - etiology
Liver Cirrhosis - surgery
Liver Function Tests
Liver Neoplasms - epidemiology
Male
Middle Aged
Prospective Studies
Retrospective Studies
Severity of Illness Index
Splenectomy - methods
Surgery
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background We aimed to assess the short-term outcomes of laparoscopic splenectomy (LS) and liver function at 1 year after splenectomy in the patients with liver cirrhosis. Methods Forty-five patients with liver cirrhosis and hypersplenism underwent LS. We reviewed electronic medical records regarding the liver functional reserve, the etiology of liver cirrhosis, and the presence of hepatocellular carcinoma and esophago-gastric varices. Prospectively collected data of perioperative variables, postoperative complications, and long-term liver function were analyzed. Results Forty-five patients had a chronic liver disease classified into Child-Pugh classes (A/B/C: 23/20/2). The etiologies of disease were hepatitis C virus infection in 34 patients, hepatitis B virus infection in 4, and others in 7. Fourteen patients underwent procedures in addition to LS, including hepatectomy ( n  = 7) and devascularization for esophagogastric varices ( n  = 8). Postoperative complications occurred in 11 patients (24%). Neither postoperative liver failure nor in-hospital mortality occurred. White blood cell and platelet counts determined 7 days, 1 month, and 1 year after LS doubled or increased more than twice compared with the preoperative values ( P  
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2015.05.008