Heat stress-induced transcriptional repression

Heat stress is one of the most popular models for studying the regulation of gene expression. For decades, researchers’ attention was focused on the study of the mechanisms of transcriptional activation of stress-induced genes. Although the phenomenon of heat stress-induced global transcriptional re...

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Bibliographic Details
Published in:Biochemistry (Moscow) 2015-08, Vol.80 (8), p.990-993
Main Authors: Kantidze, O. L., Velichko, A. K., Razin, S. V.
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Gene expression
Genetic aspects
Genetic transcription
Health aspects
Heat
Heat stress disorders
Heat tolerance
Heat-Shock Proteins - genetics
Heat-Shock Proteins - metabolism
Heat-Shock Response - genetics
Hot Temperature
Life Sciences
Microbiology
Mini-Review
Observations
Promoter Regions, Genetic
RNA polymerase
RNA polymerases
Stress
Transcription, Genetic - physiology
Transcriptional Activation
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Summary:Heat stress is one of the most popular models for studying the regulation of gene expression. For decades, researchers’ attention was focused on the study of the mechanisms of transcriptional activation of stress-induced genes. Although the phenomenon of heat stress-induced global transcriptional repression is known for a long time, the exact molecular mechanisms of such a repression are poorly explored. In this mini-review, we attempt to summarize the existing experimental data on heat stress-induced transcriptional repression.
ISSN:0006-2979
1608-3040
DOI:10.1134/S0006297915080039