Surgical Resection of Primary Tumor in Asymptomatic or Minimally Symptomatic Patients With Stage IV Colorectal Cancer: A Canadian Province Experience

Micro-Abstract Surgical removal of the primary tumor in asymptomatic or minimally symptomatic patients with stage IV colorectal cancer (CRC) and unresectable metastases remains controversial. Survival benefit reported in the literature has been attributed to the selection of younger and healthier pa...

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Bibliographic Details
Published in:Clinical colorectal cancer 2015-12, Vol.14 (4), p.e41-e47
Main Authors: Ahmed, Shahid, Fields, Anthony, Pahwa, Punam, Chandra-Kanthan, Selliah, Zaidi, Adnan, Le, Duc, Haider, Kamal, Reeder, Bruce, Leis, Anne
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Asymptomatic patients
Cohort Studies
Colorectal Neoplasms - drug therapy
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Combined Modality Therapy
Female
Gastroenterology and Hepatology
Hematology, Oncology and Palliative Medicine
Humans
Male
Middle Aged
Multivariate Analysis
Neoplasm Staging
Primary tumor
Prognosis
Proportional Hazards Models
Saskatchewan
Stage IV colorectal cancer
Surgery
Survival
Survival Rate
Treatment Outcome
Young Adult
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Summary:Micro-Abstract Surgical removal of the primary tumor in asymptomatic or minimally symptomatic patients with stage IV colorectal cancer (CRC) and unresectable metastases remains controversial. Survival benefit reported in the literature has been attributed to the selection of younger and healthier patients with good performance status. In the present study we showed that resection of the primary tumor improved survival in patients with stage IV CRC, independent of age, performance status, comorbid illness, and chemotherapy.
ISSN:1533-0028
1938-0674
DOI:10.1016/j.clcc.2015.05.008