Interferences of an environmental pollutant with estrogen-like action in the male reproductive system of the terrestrial vertebrate Podarcis sicula

Highlights • NP polluted diet affects the morpho-physiology of the testis and epididymis. • NP interferes with the expression of estrogen and androgen receptors in the testis. • NP switches off the secretion of the epididymal channel through ERα expression. • The lizard Podarcis sicula is a good bio...

Full description

Saved in:
Bibliographic Details
Published in:General and comparative endocrinology 2015-03, Vol.213, p.9-15
Main Authors: Verderame, Mariailaria, Limatola, Ermelinda
Format: Article
Language:English
Subjects:
Animals
Diet
Endocrinology & Metabolism
Environmental Pollutants - pharmacology
Epididymis
Epididymis - drug effects
Epididymis - metabolism
Estrogen Receptor alpha - genetics
Estrogen Receptor alpha - metabolism
Estrogen Receptor beta - genetics
Estrogen Receptor beta - metabolism
Estrogens - pharmacology
Histological Techniques
In Situ Hybridization
Lacertilia
Lizards - metabolism
Male
Nonylphenol
Phenols - pharmacology
Podarcis sicula
Receptors, Androgen - genetics
Receptors, Androgen - metabolism
Reproduction - drug effects
Reptiles
Spermatogenesis - drug effects
Spermatogenesis - physiology
Steroid receptors
Testis
Testis - drug effects
Testis - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • NP polluted diet affects the morpho-physiology of the testis and epididymis. • NP interferes with the expression of estrogen and androgen receptors in the testis. • NP switches off the secretion of the epididymal channel through ERα expression. • The lizard Podarcis sicula is a good bio-indicator of environmental pollution.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2015.01.027