Increased expression of MMP14 correlates with the poor prognosis of Chinese patients with gastric cancer

The role of matrix metalloproteinase 14 (MMP14) has been identified to involve tumor progression and prognosis. The purpose of this study is to investigate the role of MMP14 in tumor progression and prognosis of gastric cancer. This study indicated that MMP14 mRNA and protein were overexpressed in g...

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Bibliographic Details
Published in:Gene 2015-05, Vol.563 (1), p.29-34
Main Authors: Dong, Yichen, Chen, Guohua, Gao, Mingming, Tian, Xia
Format: Article
Language:English
Subjects:
Aged
Asian Continental Ancestry Group - genetics
Female
Gastric cancer
Gene Expression Regulation, Neoplastic
Humans
Immunohistochemistry
Lymphatic Metastasis - genetics
Male
Matrix Metalloproteinase 14 - genetics
Matrix Metalloproteinase 14 - metabolism
Meta-analysis
Middle Aged
MMP14
Prognosis
Reference Values
Stomach Neoplasms - genetics
Stomach Neoplasms - mortality
Stomach Neoplasms - pathology
Survival Analysis
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Description
Summary:The role of matrix metalloproteinase 14 (MMP14) has been identified to involve tumor progression and prognosis. The purpose of this study is to investigate the role of MMP14 in tumor progression and prognosis of gastric cancer. This study indicated that MMP14 mRNA and protein were overexpressed in gastric cancer tissue (P
ISSN:0378-1119
1879-0038
DOI:10.1016/j.gene.2015.03.003