Bilayered (silica–chitosan) coatings for studying dye release in aqueous media: The role of chitosan properties

•Properties of chitosan coatings were studied by developing a bi-layer model system.•Wettability tests gave information about the mobility of surface polymer segments.•Swelling tests gave information about the mobility of bulk polymer segments.•Both cross-linked chitosan coatings showed lowered perm...

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Bibliographic Details
Published in:Carbohydrate polymers 2016-01, Vol.136, p.137-145
Main Authors: Dabóczi, Mátyás, Albert, Emőke, Agócs, Emil, Kabai-Faix, Márta, Hórvölgyi, Zoltán
Format: Article
Language:English
Subjects:
Bilayered coatings
Chitosan - chemistry
Coloring Agents - chemistry
Contact angle
Cross-linked chitosan
Delayed-Action Preparations
Drug Carriers - chemistry
Dye release
Ellipsometry
Humans
Hydrogen-Ion Concentration
Permeability
Porosity
Rhodamines - chemistry
Silicon Dioxide - chemistry
Swelling
Water - chemistry
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Summary:•Properties of chitosan coatings were studied by developing a bi-layer model system.•Wettability tests gave information about the mobility of surface polymer segments.•Swelling tests gave information about the mobility of bulk polymer segments.•Both cross-linked chitosan coatings showed lowered permeability for cationic dye.•Permeability was interpreted by the wetting and swelling properties of chitosan. Chitosan and bilayered – Rhodamine 6G impregnated silica–chitosan – coatings (300–3000nm thick) were prepared and investigated as a model for controlled drug release. Properties of native, ionically (sodium triphosphate) and covalently (glutaraldehyde) cross-linked layers of chitosan in contact with aqueous phase (modeling human blood pH of ca. 7.3) were investigated. The cross-linking was confirmed by attenuated total reflection (ATR) Fourier transform infrared (FTIR), energy-dispersive spectroscopy (EDS) and solid state 13C nuclear magnetic resonance (NMR) spectroscopy. The evolution of advancing water contact angles as a function of time was measured, and from the results restricted mobility of polymer segments in the interfacial layer of cross-linked chitosan coatings were assumed. Spectroscopic ellipsometry measurements showed that covalent cross-linking leads to a lowered, while ionic cross-linking to an increased swelling degree of chitosan layers. Despite the swelling behavior both cross-linked chitosan layers showed significant retard effect on dye release from the bilayered coatings.
ISSN:0144-8617
1879-1344
DOI:10.1016/j.carbpol.2015.09.025