Evaluation of arterial stiffness in elderly with prehypertension

Arterial stiffness is an independent marker of cardiovascular (CV) risk that increases with age. Hypertension is known to augment the age-related arterial stiffness. The influence of prehypertension on arterial stiffness in elderly is least studied. The present study was aimed to assess the age-asso...

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Bibliographic Details
Published in:Indian journal of physiology and pharmacology 2015-01, Vol.59 (1), p.16-22
Main Authors: Gurunathrao, Patil Satish, Manjunatha, Aithala, Kanti, Das Kusal
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Ankle Brachial Index
Blood Pressure
Cross-Sectional Studies
Humans
Male
Middle Aged
Prehypertension - physiopathology
Vascular Stiffness - physiology
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Summary:Arterial stiffness is an independent marker of cardiovascular (CV) risk that increases with age. Hypertension is known to augment the age-related arterial stiffness. The influence of prehypertension on arterial stiffness in elderly is least studied. The present study was aimed to assess the age-associated arterial stiffness in the elderly subjects with prehypertension. A cross sectional study was conducted on elderly subjects aged 60-80 years with prehypertension (n=25) and age-matched normotensives (n=20). The arterial stiffness was assessed by measuring: (1) Pulse wave velocity between carotid-femoral (c-f PWV) and brachial-ankle (baPWV) (2) Augmentation index (AIx) and (3) Arterial stiffness index (ASI) at brachial (bASI) and tibial artery (aASI). We found a significant increase in c-f PWV (p
ISSN:0019-5499