Luteolin as an anti-inflammatory and neuroprotective agent: A brief review

Highlights • Neurodegenerative diseases are leading causes of age related-morbidity and mortality. • Extensive research suggests the therapeutic role of dietary phytochemicals for the treatment of neurological disorders. • Luteolin suppresses inflammation and regulates different cell signaling pathw...

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Bibliographic Details
Published in:Brain research bulletin 2015-10, Vol.119 (Pt A), p.1-11
Main Authors: Nabavi, Seyed Fazel, Braidy, Nady, Gortzi, Olga, Sobarzo-Sanchez, Eduardo, Daglia, Maria, Skalicka-Woźniak, Krystyna, Nabavi, Seyed Mohammad
Format: Article
Language:English
Subjects:
Alzheimer’s disease
Animals
Anti-Inflammatory Agents - pharmacology
Anti-Inflammatory Agents - therapeutic use
Flavonoid
Humans
Luteolin
Luteolin - pharmacology
Luteolin - therapeutic use
Neurology
Neuroprotective Agents - pharmacology
Neuroprotective Agents - therapeutic use
Neurotoxicity
Oxidative stress
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Summary:Highlights • Neurodegenerative diseases are leading causes of age related-morbidity and mortality. • Extensive research suggests the therapeutic role of dietary phytochemicals for the treatment of neurological disorders. • Luteolin suppresses inflammation and regulates different cell signaling pathways. • Improved formulations may overcome issues with bioavailability, metabolism, and toxicity.
ISSN:0361-9230
1873-2747
DOI:10.1016/j.brainresbull.2015.09.002