The 3-second auditory conditioned stimulus is a more effective stressor than the 20-second auditory conditioned stimulus in male rats

Highlights • The 3-s and 20-s auditory CS induced phasic and sustained fear responses, respectively. • The 20-s CS induced either sustained or phasic fear responses depending on the intensity of foot shock paired with it. • The fear response elicited by the 3-s CS is more resistant to extinction tha...

Full description

Saved in:
Bibliographic Details
Published in:Neuroscience 2015-07, Vol.299, p.79-87
Main Authors: Kiyokawa, Y, Mikami, K, Mikamura, Y, Ishii, A, Takeuchi, Y, Mori, Y
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Amygdala - drug effects
Amygdala - physiology
Animals
auditory fear conditioning
bed nucleus of the stria terminalis
Conditioning, Classical - physiology
corticosterone
CS duration
Fear - physiology
foot shock intensity
Ibotenic Acid
Male
Neurology
Rats
Rats, Wistar
Septal Nuclei - drug effects
Septal Nuclei - physiology
Stress, Psychological - physiopathology
sustained fear response
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • The 3-s and 20-s auditory CS induced phasic and sustained fear responses, respectively. • The 20-s CS induced either sustained or phasic fear responses depending on the intensity of foot shock paired with it. • The fear response elicited by the 3-s CS is more resistant to extinction than the fear response during the 20-s CS. • The 3-s CS elicited more intense fear and stress responses than the 20-s CS.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2015.04.055