Canid herpesvirus 1 (CHV-1)–related disease in older puppies and CHV-1 shedding in the vagina of adult pregnant dogs

A large breeding kennel of Bulldogs (n = 57) experienced several Canid herpesvirus 1 (CHV-1)–related diseases in older puppies (9 weeks of age) in Arkansas. CHV-1 has been repeatedly confirmed in the kennel in several animals for 3 years (January 2012–February 2015) using various virology tests. I w...

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Bibliographic Details
Published in:Journal of veterinary diagnostic investigation 2015-11, Vol.27 (6), p.758-761
Main Author: Kapil, Sanjay
Format: Article
Language:English
Subjects:
Age Factors
Animals
Arkansas
DNA, Viral - analysis
Dog Diseases - diagnosis
Dog Diseases - virology
Dogs
Female
Herpesviridae Infections - diagnosis
Herpesviridae Infections - veterinary
Herpesviridae Infections - virology
Herpesvirus 1, Canid
Male
Pregnancy
Species Specificity
Vagina - virology
Virus Shedding
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Summary:A large breeding kennel of Bulldogs (n = 57) experienced several Canid herpesvirus 1 (CHV-1)–related diseases in older puppies (9 weeks of age) in Arkansas. CHV-1 has been repeatedly confirmed in the kennel in several animals for 3 years (January 2012–February 2015) using various virology tests. I was able to detect a partial sequence of CHV DNA (~120 bp) in archived formalin-fixed, paraffin-embedded tissue blocks after 3 years of storage. CHV-1 is persistently circulating in this kennel in spite of high serum antibody titers in the adult dogs. The dogs were negative for canine brucellosis antibodies based on Brucella canis rapid card test.
ISSN:1040-6387
1943-4936
DOI:10.1177/1040638715610377