A prospective, randomized, blinded assessment of multitarget thalamic and pallidal deep brain stimulation in a case of hemidystonia

Highlights • Thalamic, pallidal and multi-target DBS was tested for stroke-induced hemi-dystonia. • Multi-target DBS was most effective as measured by the BFMDRS and SF-36. • Multi-target DBS needs further investigation in intractable secondary dystonia.

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2015-11, Vol.138, p.16-19
Main Authors: Slotty, Philipp J, Poologaindran, Anujan, Honey, Christopher R
Format: Article
Language:English
Subjects:
Conflicts of interest
Deep brain stimulation
Deep Brain Stimulation - methods
Double-Blind Method
Dystonic Disorders - etiology
Dystonic Disorders - physiopathology
Dystonic Disorders - therapy
Electrodes
Electrodes, Implanted
Female
Globus Pallidus - physiology
Hemidystonia
Humans
Multitarget
Neurology
Neurosurgery
Pain
Pallidal
Putaminal Hemorrhage - complications
Quality of life
Quality of Life - psychology
Random Allocation
Secondary dystonia
Stroke
Thalamic
Thalamus - physiology
Young Adult
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Description
Summary:Highlights • Thalamic, pallidal and multi-target DBS was tested for stroke-induced hemi-dystonia. • Multi-target DBS was most effective as measured by the BFMDRS and SF-36. • Multi-target DBS needs further investigation in intractable secondary dystonia.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2015.07.012