The renaissance of 2,4,6-tris(2-pyrimidyl)-1,3,5-triazine (TPymT) coordination chemistry

• Published in: Dalton transactions : an international journal of inorganic chemistry 2015-01, Vol.44 (47), p.2287-2294
• Main Authors: Safin, Damir A, Frost, Jamie M, Murugesu, Muralee
• Format: Article
• Language: English
• Subjects: Catalysis; Coordination compounds; Crystals; Hydrolysis; Ligands; Pocket; Porous materials; Stands
• ISSN: 1477-9226; 1477-9234
• DOI: 10.1039/c5dt03435c

In this perspective we report on recently accumulated data on the synthesis and coordination chemistry of 2,4,6-tris(2-pyrimidyl)-1,3,5-triazine (TPymT). Although a highly attractive ligand, owing to the presence of three fused terpyridine-like coordination pockets, the coordination chemistry of TPymT has something of a chequered past. This can principally be attributed to the hydrolysis of the ligand, which readily occurs under mild conditions. Thus, after first being synthesised in 1959 it had only been used a handful of times to synthesise coordination compounds until we began reinvestigating its chemistry in early 2013. Despite the significant challenges associated with its use, our work over the past two years has demonstrated that coordination chemistry with TPymT is indeed possible. Herein, we describe an overview of this body of work as it stands, and discuss its potential impact in a variety of areas including porous materials, catalysis and crystal engineering. In this perspective we report on recently accumulated data on the synthesis and coordination chemistry of 2,4,6-tris(2-pyrimidyl)-1,3,5-triazine (TPymT).