Malignant peripheral nerve sheath tumors of the head and neck: Demographics, clinicopathologic features, management, and treatment outcomes

Highlights • The SEER database was queried for patients with MPNST of the head and neck. • Clinicopathologic and therapeutic determinants of patient survival were analyzed. • Surgical resection confers survival benefit in patients stage I/II MPNST. • Radiation therapy confers survival benefit in pat...

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Bibliographic Details
Published in:Oral oncology 2015-12, Vol.51 (12), p.1088-1094
Main Authors: Arshi, Armin, Tajudeen, Bobby A, St. John, Maie
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Disease-Free Survival
Female
Head and neck cancer
Head and Neck Neoplasms - mortality
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - therapy
Hematology, Oncology and Palliative Medicine
Humans
Infant
Infant, Newborn
Kaplan-Meier Estimate
Logistic Models
Male
Malignant
Middle Aged
MPNST
Nerve
Neurilemmoma - mortality
Neurilemmoma - pathology
Neurilemmoma - therapy
Oral cancer
Otolaryngology
Peripheral
Risk Factors
SEER
SEER Program
Survival Rate
Treatment Outcome
Tumor
Young Adult
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Summary:Highlights • The SEER database was queried for patients with MPNST of the head and neck. • Clinicopathologic and therapeutic determinants of patient survival were analyzed. • Surgical resection confers survival benefit in patients stage I/II MPNST. • Radiation therapy confers survival benefit in patients with stage III/IV MPNST. • A critical tumor size cutoff of 5 cm for predicting patient outcomes was identified.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2015.08.012