Single organ metastatic disease and local disease status, prognostic factors for overall survival in stage IV non-small cell lung cancer: Results from a population-based study

Highlights • OS significantly longer in single organ metastatic disease compared to 2 or ⩾3 organs. • Single organ metastases also prognostic in subgroup of18 FDG-PET-staged patients. • Single organ metastases also prognostic in patients receiving anticancer treatment. • In single organ metastases,...

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Bibliographic Details
Published in:European journal of cancer (1990) 2015-11, Vol.51 (17), p.2534-2544
Main Authors: Hendriks, L.E, Derks, J.L, Postmus, P.E, Damhuis, R.A, Houben, R.M.A, Troost, E.G.C, Hochstenbag, M.M, Smit, E.F, Dingemans, A.-M.C
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Aged
Bone Neoplasms - secondary
Brain Neoplasms - secondary
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Squamous Cell - pathology
Female
Fluorodeoxyglucose F18
Hematology, Oncology and Palliative Medicine
Humans
Kaplan-Meier Estimate
Liver Neoplasms - secondary
Local disease status
Lung Neoplasms - pathology
Lymphatic Metastasis
Male
Metastases
Middle Aged
Multimodal Imaging - methods
Multimodal Imaging - statistics & numerical data
Neoplasm Recurrence, Local
Neoplasm Staging
Non-small cell lung cancer
Positron-Emission Tomography
Prognosis
Proportional Hazards Models
Stage IV
Tomography, X-Ray Computed
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Summary:Highlights • OS significantly longer in single organ metastatic disease compared to 2 or ⩾3 organs. • Single organ metastases also prognostic in subgroup of18 FDG-PET-staged patients. • Single organ metastases also prognostic in patients receiving anticancer treatment. • In single organ metastases, low local disease (i.e. T1–2 and N0–1) best prognosis.
ISSN:0959-8049
1879-0852
DOI:10.1016/j.ejca.2015.08.008