Imaging morphological changes of intraductal papillary mucinous neoplasm of the pancreas was associated with its malignant transformation but not with development of pancreatic ductal adenocarcinoma

Abstract Background/objective A considerable number of branch duct intraductal papillary mucinous neoplasm (BD-IPMN) developed not infrequently pancreatic malignancy, either as part of IPMN (malignant IPMN) or as concomitant pancreatic ductal adenocarcinoma (PDAC). To date, imaging morphological cha...

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Bibliographic Details
Published in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2015-11, Vol.15 (6), p.654-660
Main Authors: Kawada, Natsuko, Uehara, Hiroyuki, Nagata, Shigenori, Tsuchishima, Mutsumi, Tsutsumi, Mikihiro, Tomita, Yasuhiko
Format: Article
Language:English
Subjects:
Adenocarcinoma, Mucinous - pathology
Aged
Antigens
Carcinoma, Papillary - pathology
Cell Transformation, Neoplastic - pathology
Cellular biology
Concomitant PDAC
Confidence intervals
Cysts
Endocrinology & Metabolism
Endoscopy
Female
Fukuoka guidelines
Gastroenterology and Hepatology
Growth rate
Humans
IPMN
Male
Malignant transformation
Methods of follow-up
Middle Aged
Morphological changes
Morphology
NMR
Nuclear magnetic resonance
Pancreas
Pancreatic Neoplasms - pathology
Surveillance
Tumors
Ultrasonic imaging
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Summary:Abstract Background/objective A considerable number of branch duct intraductal papillary mucinous neoplasm (BD-IPMN) developed not infrequently pancreatic malignancy, either as part of IPMN (malignant IPMN) or as concomitant pancreatic ductal adenocarcinoma (PDAC). To date, imaging morphological changes predicting occurrence of malignancy in BD-IPMN are not well-investigated. This study aimed to evaluate the relationships between occurrence of malignancy in BD-IPMN and imaging morphological changes of the tumors observed during follow-up. Methods 515 BD-IPMN patients with mural nodule
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2015.08.004