H. pylori positivity and various pathological, endoscopic and clinical features correlated with each other

To investigate the relationship between dyspepsia symptom scores and endoscopic appearances, and histopathological findings and helicobacter pylori positivity in patients having dyspepsia symptom. The study was conducted at the gastroenterology outpatient clinic of Adnan Menderes University, School...

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Bibliographic Details
Published in:Journal of the Pakistan Medical Association 2015-12, Vol.65 (12), p.1305-1309
Main Authors: Coskun, Adil, Yukselen, Vahit, Meteoglu, Ibrahim, Ergin, Filiz, Kadikoylu, Gurhan, Yasa, Mehmet Hadi, Karaoglu, Ali Onder
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Cells (Biology)
Cohort Studies
Dyspepsia - microbiology
Dyspepsia - pathology
Endoscopy, Gastrointestinal
Female
Helicobacter Infections - complications
Helicobacter Infections - pathology
Helicobacter pylori
Humans
Male
Middle Aged
Turkey
Young Adult
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Summary:To investigate the relationship between dyspepsia symptom scores and endoscopic appearances, and histopathological findings and helicobacter pylori positivity in patients having dyspepsia symptom. The study was conducted at the gastroenterology outpatient clinic of Adnan Menderes University, School of Medicine, Aydin, Turkey from April 2012 to July 2012 and comprised patients between 18-65 years of age who were admitted with dyspepsia. Glasgow dyspepsia severity scoring was done with questions posed orally to the patients. In histopathological evaluation of biopsy specimens according to Sydney criteria, chronic inflammation, activity, atrophy, intestinal metaplasia and helicobacter pylori parameters were used. Total number of eosinophils and number of mast cells were recorded. Of the 60 patients with dyspepsia, 38(63.3%) were female and 22(36.7%) were male. The degree of activation and severity of inflammation increased significantly with increasing helicobacter pylori positivity(r=0.459'p
ISSN:0030-9982