Toxicological Analysis of Sulpiride in a Lethal Poisoning Case

A fatality following ingestion of sulpiride is presented. The drug was identified and quantitated in postmortem blood by gas chromatography-mass spectrometry and high-performance liquid chromatography with diode-array detection. The concentration was 38 µg/mL, which was in excess of 34 times the the...

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Bibliographic Details
Published in:Journal of analytical toxicology 1999-07, Vol.23 (4), p.294-296
Main Authors: Rop, Pok P., Sournac, Marie H., Elie, Isabelle, Burle, Joëlle, Fornaris, Monique
Format: Article
Language:English
Subjects:
Adult
Antipsychotic Agents - analysis
Antipsychotic Agents - poisoning
Biological and medical sciences
Drug intoxications. Doping
Drug Overdose
Fatal Outcome
Female
Gas Chromatography-Mass Spectrometry
Humans
Medical sciences
Pharmacology. Drug treatments
sulpiride
Sulpiride - analysis
Sulpiride - poisoning
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Summary:A fatality following ingestion of sulpiride is presented. The drug was identified and quantitated in postmortem blood by gas chromatography-mass spectrometry and high-performance liquid chromatography with diode-array detection. The concentration was 38 µg/mL, which was in excess of 34 times the therapeutic concentration of sulpiride. For other associated drugs, their concentrations were in their therapeutic ranges.
ISSN:0146-4760
1945-2403
DOI:10.1093/jat/23.4.294